He was already said to be doomed by two serious illnesses. Yet, this 63-year-old man is now in complete remission from both HIV and cancer - an outcome made possible by a series of coincidences so extraordinary that even his doctors are still struggling to grasp their significance.<\/p>\n
The "Oslo patient," whose identity is being withheld, has been living with HIV since 2006. His viral load had been well controlled with antiretroviral therapy until then. However, in 2017, he received a new diagnosis: myelodysplastic syndrome, a particularly aggressive blood cancer that disrupts blood cell production in the bone marrow. Without a transplant, his life was virtually at risk.<\/p>\n
The medical team at Oslo University Hospital then began an intensive search for a compatible donor. Their initial strategy focused on identifying a donor carrying the CCR5-delta32 mutation, a rare genetic anomaly that confers natural resistance to HIV\u2014a trait possessed by only about 1% of the Northern European population. Faced with the failure of this first approach, the doctors turned to the patient's older brother, hoping for a better genetic match.<\/p>\n
On the day of the transplant in 2020, doctors were stunned to discover that the donor brother himself carried the CCR5 mutation. A minuscule chance, in a region of the world where it affects only one in a hundred people. The patient himself summed up the situation with a striking phrase: "It was like winning the lottery twice."<\/em><\/p>\n Post-operative analyses gradually confirmed the transplant's effectiveness. Two years after the procedure, the "Oslo Patient" discontinued his antiretroviral treatments under strict medical supervision. Subsequent tests then detected no further viral traces in his blood, intestines, or spinal cord. His case was officially detailed<\/a> in a study published on April 13, 2026, in the journal Nature Microbiology.<\/p>\n The "Oslo patient" joins a very small international list\u2014the so-called Berlin, London, D\u00fcsseldorf, New York, City of Hope, and Geneva patients\u2014all considered cured or in sustained remission from HIV following a bone marrow transplant intended to treat cancer. They all share the same characteristic: a donor carrying the protective CCR5 mutation, with the notable exception of the Geneva patient, whose case explores other mechanisms.<\/p>\n However, the researchers and physicians involved urge extreme caution. Bone marrow transplantation remains a complex and risky procedure, associated with significant mortality and very serious side effects. Its mortality rate can reach 20% in certain circumstances. Nevertheless, these cases remain invaluable "living laboratories" for research, offering avenues for understanding the mechanisms that could one day allow us to control or even permanently eradicate HIV.<\/p>\n In summary, this patient, nicknamed "Oslo Patient," defies medical statistics. His story illustrates how certain therapeutic advances arise from exceptional circumstances, where biology, medicine, and chance intersect in an almost unrepeatable way.<\/p>\n","protected":false},"excerpt":{"rendered":"He was already said to be doomed by two serious illnesses. Yet, this 63-year-old man is now in...","protected":false},"author":8375,"featured_media":439738,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"disable_msn":false,"footnotes":""},"categories":[5639],"tags":[],"class_list":["post-439713","post","type-post","status-publish","format-standard","has-post-thumbnail","category-bien-etre"],"image":{"medium":["https:\/\/www.ma-grande-taille.com\/wp-content\/uploads\/2026\/04\/Charlss-GonzHu-_-Pexels-200x113.jpg",200,113,true],"large":["https:\/\/www.ma-grande-taille.com\/wp-content\/uploads\/2026\/04\/Charlss-GonzHu-_-Pexels-500x281.jpg",500,281,true]},"custom":{"td_video":"","featured_image":"https:\/\/www.ma-grande-taille.com\/wp-content\/uploads\/2026\/04\/Charlss-GonzHu-_-Pexels.jpg","author":{"name":"Fabienne Baure","avatar":"https:\/\/www.ma-grande-taille.com\/wp-content\/uploads\/2026\/10\/fabienne_baure-96x96.jpg"},"categories":[{"term_id":5639,"name":"Well-being","slug":"bien-etre","term_group":0,"term_taxonomy_id":5804,"taxonomy":"category","description":" The Well-being section of The Body Optimist shares practical advice on staying active, sleeping better, managing stress and understanding everyday aches and pains. Written for women of every size and body type, it starts from a simple idea: taking care of your body works best through enjoyment and consistency, not pressure or guilt.<\/p>\n When you return to physical activity, consistency matters more than intensity. A few ways to ease back in:<\/p>\n Everyday movement counts too: walking or biking to get around, taking the stairs and gardening all add up as physical activity.<\/p>\n Here, your body isn't a project to fix. We talk about exercise for pleasure, mood and health, never as a way to \u201cmake up for\u201d a meal or to lose weight, and every tip should work for you whatever your body type. The articles in this section provide general information and do not replace advice from a healthcare professional.<\/p>\n The World Health Organization recommends that adults get at least 150 minutes of moderate-intensity aerobic activity per week, such as brisk walking. It also stresses that some activity is better than none: every session counts, even a short one, and what matters most is finding a pace you can keep up over the long run.<\/p>\n Consistency is the first lever: go to bed and get up at similar times, weekends included. A quiet, dark, cool bedroom, less screen time in the evening and a dinner that isn't too late all make it easier to fall asleep. Loud snoring or waking up gasping for air is worth mentioning to your doctor.<\/p>\n Ongoing fatigue can have many causes: lack of sleep, stress or mental overload, but also iron deficiency, a thyroid disorder or depression. If it lasts several weeks despite rest, or comes with other symptoms, see your doctor to find out what's behind it.<\/p>\n Want to go further? Explore all our topics in the Health section<\/a>, follow moms-to-be in the Pregnancy section<\/a> and enjoy a varied way of eating, without restriction, with the Nutrition section<\/a>.<\/p>","parent":360,"count":1718,"filter":"raw","cat_ID":5639,"category_count":1718,"category_description":" The Well-being section of The Body Optimist shares practical advice on staying active, sleeping better, managing stress and understanding everyday aches and pains. Written for women of every size and body type, it starts from a simple idea: taking care of your body works best through enjoyment and consistency, not pressure or guilt.<\/p>\n When you return to physical activity, consistency matters more than intensity. A few ways to ease back in:<\/p>\n Everyday movement counts too: walking or biking to get around, taking the stairs and gardening all add up as physical activity.<\/p>\n Here, your body isn't a project to fix. We talk about exercise for pleasure, mood and health, never as a way to \u201cmake up for\u201d a meal or to lose weight, and every tip should work for you whatever your body type. The articles in this section provide general information and do not replace advice from a healthcare professional.<\/p>\n The World Health Organization recommends that adults get at least 150 minutes of moderate-intensity aerobic activity per week, such as brisk walking. It also stresses that some activity is better than none: every session counts, even a short one, and what matters most is finding a pace you can keep up over the long run.<\/p>\n Consistency is the first lever: go to bed and get up at similar times, weekends included. A quiet, dark, cool bedroom, less screen time in the evening and a dinner that isn't too late all make it easier to fall asleep. Loud snoring or waking up gasping for air is worth mentioning to your doctor.<\/p>\n Ongoing fatigue can have many causes: lack of sleep, stress or mental overload, but also iron deficiency, a thyroid disorder or depression. If it lasts several weeks despite rest, or comes with other symptoms, see your doctor to find out what's behind it.<\/p>\n Want to go further? Explore all our topics in the Health section<\/a>, follow moms-to-be in the Pregnancy section<\/a> and enjoy a varied way of eating, without restriction, with the Nutrition section<\/a>.<\/p>","cat_name":"Well-being","category_nicename":"bien-etre","category_parent":360}]},"_links":{"self":[{"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/posts\/439713","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/users\/8375"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/comments?post=439713"}],"version-history":[{"count":3,"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/posts\/439713\/revisions"}],"predecessor-version":[{"id":439775,"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/posts\/439713\/revisions\/439775"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/media\/439738"}],"wp:attachment":[{"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/media?parent=439713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/categories?post=439713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ma-grande-taille.com\/en\/wp-json\/wp\/v2\/tags?post=439713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}} A confirmed remission, two years after the operation<\/h2>\n
One more name on a very short list<\/h2>\n
A medical hope, but not a treatment that can be widely used<\/h2>\n
What you'll find in the Well-being section<\/h2>\n
\n
How do you get back into exercise after a long break?<\/h2>\n
\n
Our approach<\/h2>\n
Articles to get you started<\/h2>\n
\n
Frequently asked questions<\/h2>\n
How much exercise do you need each week?<\/h3>\n
How can you sleep better?<\/h3>\n
Why am I tired all the time?<\/h3>\n
What you'll find in the Well-being section<\/h2>\n
\n
How do you get back into exercise after a long break?<\/h2>\n
\n
Our approach<\/h2>\n
Articles to get you started<\/h2>\n
\n
Frequently asked questions<\/h2>\n
How much exercise do you need each week?<\/h3>\n
How can you sleep better?<\/h3>\n
Why am I tired all the time?<\/h3>\n